Benign ethnic neutropenia

Clozapine, agranulocytosis, and benign ethnic neutropenia.

C lozapine is an atypical antipsychotic that is effective in treatment resistant schizophrenia. The National Institute for Health and Clinical Excellence (NICE) guidelines for schizophrenia specify that ‘‘in individuals with evidence of treatment resistant schizophrenia, clozapine should be introduced at the earliest opportunity’’. A severe adverse effect of clozapine that limits its more wides...

Chronic benign neutropenia among Chinese children.

OBJECTIVE To delineate the clinical behaviour of chronic benign neutropenia in Chinese children in Hong Kong. DESIGN Retrospective study. SETTING University teaching hospital, Hong Kong. PATIENTS All infants and children with absolute neutrophil count of 1.5 x 10(9) /L or lower for more than 3 months. MAIN OUTCOME MEASURES Development of significant infection, and achievement of remissi...

A Case of Benign Neutropenia Treated by Sodium Pentnucleotide

Prevalence, phenotype and inheritance of benign neutropenia in Arabs

BACKGROUND Benign neutropenia, i.e., neutropenia not associated with an increased risk of infection, may result in serious medical consequences when a 'standard' definition of neutropenia (absolute neutrophil count (ANC) < 1.5 x 10(9)cells/L) is universally applied to all races. The aims of this study were to determine the prevalence of benign neutropenia among healthy Arabs and evaluate its mo...

Prevalence of neutropenia in the U.S. population: age, sex, smoking status, and ethnic differences.

BACKGROUND Benign reductions in neutrophil counts may be more common at certain ages and in certain ethnic groups and may be affected by sex and smoking status. OBJECTIVE To determine differences in neutrophil counts in the U.S. population according to ethnicity, age, sex, and smoking status. DESIGN Population-based, cross-sectional study. SETTING Various locations in the United States. ...